解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::A double-blind 3-year clinical trial was conducted in a nonfluoridated water community in which 354 schoolchildren aged 9-10 years were assigned randomly to three groups (A, B and C) and subjected to a treatment with 1 of 3 different concentrations of amine fluoride solution every 2 months. Clinical examinations were ...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000262064
更新日期:1995-01-01 00:00:00
abstract::The influence of air-drying on the remineralization of demineralized bovine dentine was examined in wet bulk samples, in dried bulk samples as well as in wet thin sections. Bulk samples of bovine dentine were first demineralized in an acidic gel (pH = 5) at 37 degrees C for 3 weeks. After 24-hour pre-treatment of eith...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000262074
更新日期:1995-01-01 00:00:00
abstract::The aim of this study was to assess the relationship between salivary mutans streptococcus (SMS) levels and the prevalence and incidence of dental caries in 148 children (mean baseline age 3.8 years) of low socioeconomic status. Caries data (dmfs) and semiquantitative SMS counts were obtained at baseline and annually ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000262057
更新日期:1995-01-01 00:00:00
abstract::An occlusal restoration is usually considered necessary when a lesion extends into the dentin. This study aimed to assess the relationship between the clinical appearance of occlusal caries and the lesion depth. Special attention was paid to differentiate the inner, partly demineralitzed layer of carious dentin that s...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000262003
更新日期:1994-01-01 00:00:00
abstract::The influence of temporary dietary restriction with and without fluoridated drinking water on the progression of caries was studied in 60 desalivated Sprague-Dawley rats. Dietary restriction alone had little effect on caries progression when the challenge was interrupted and then resumed, in contrast to the effects of...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261974
更新日期:1994-01-01 00:00:00
abstract::The quality of radiographic diagnosis of occlusal carries was examined with special attention to the diagnosis of lesions in dentin. Eighty-four extracted teeth, most of them with occlusal caries of different severity and some apparently sound, were radiographed. For validation purposes, the lesion depths were recorde...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261640
更新日期:1994-01-01 00:00:00
abstract::Based on the current concept of the caries-preventive mechanism of fluoride, the fluoride concentration of some professionally applied fluoride preparations appears unnecessarily high. The aim of this trial was to study whether reducing the fluoride concentration of the sodium fluoride varnish Duraphat from the presen...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000261623
更新日期:1994-01-01 00:00:00
abstract::This investigation was done to determine the bioavailability of fluoride (F) after toothbrushing associated with different water rinsing procedures. Eight adult subjects participated in four experiments, conducted with a randomised, crossover design: (A) 2 min brushing with an F dentifrice, followed by three quick (3 ...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000262020
更新日期:1994-01-01 00:00:00
abstract::The distribution of fluoride in human dental calculus was investigated using a mechanical sampling technique and the fluoride electrode. The fluoride concentrations were highest at the outer surface of dental calculus and, then fell to a plateau for the interior of the calculus, rising again as the tooth surface was a...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261549
更新日期:1993-01-01 00:00:00
abstract::There is ample evidence that caries can develop well into the middle-aged years, and for many subjects, for most of their adult lives. The kinds of benefits to expect for adults in the longer term for improved fluoride products, especially dentifrices, based upon small observed relative improvements in short-term effi...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261561
更新日期:1993-01-01 00:00:00
abstract::The effectiveness of fluoridation has been documented by observational and interventional studies for over 50 years. Data are available from 113 studies in 23 countries. The modal reduction in DMFT values for primary teeth was 40-49% and 50-59% for permanent teeth. The pattern of caries now occurring in fluoride and l...
journal_title:Caries research
pub_type: 杂志文章,评审
doi:10.1159/000261594
更新日期:1993-01-01 00:00:00
abstract::Antimicrobial agents, applied either professionally or delivered from dentifrices or mouthwashes, could reduce caries by controlling plaque formation, suppressing cariogenic species, or by inhibiting bacterial metabolism. Chlorhexidine has proven anticaries activity; other agents might also prevent caries by means of ...
journal_title:Caries research
pub_type: 杂志文章,评审
doi:10.1159/000261607
更新日期:1993-01-01 00:00:00
abstract::Mixed continuous cultures of Streptococcus species were obtained, using complex carbohydrate (mucin) as a source of nutrients, to study the ecological effects of oxygen and the lactoperoxidase system. S. mutans NCTC 10449 was unable to grow as a pure culture on mucin, but attained a significant population size in the ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261511
更新日期:1993-01-01 00:00:00
abstract::The microradiographic mineral content and birefringence in water and Thoulet's solution were measured at selected points in sections of caries-like lesions. Birefringence was not related to mineral content in sound superficial enamel immersed in Thoulet's solution or in the lesion body immersed in water. For the surfa...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261508
更新日期:1993-01-01 00:00:00
abstract::The aim of this study was to examine how dental health related habits, infectious diseases and long-term illness are associated with dental health at the age of 3 in first-born children resident in a Finnish province. The study was designed as a survey using stratified randomised cluster sampling, confidential questio...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261534
更新日期:1993-01-01 00:00:00
abstract::The effect of a glass-ionomer cement sealant on carious dentine was investigated clinically and bacteriologically. The study group consisted of 24 molar teeth, with small clinical visible occlusal dentine lesions, in 13 children (aged 7-18 years). Twenty of these molars were filled and sealed with a glass-ionomer ceme...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261573
更新日期:1993-01-01 00:00:00
abstract::Pooled plaque samples were obtained from (1) coronal surfaces of two groups of caries-free (CF) subjects, (2) coronal 'white-spot' surface areas of a group of caries-positive (CP) subjects, and (3) exposed, sound root surfaces of root caries-free (RCF) and root caries-positive (RCP) subjects. The plaque samples were o...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261582
更新日期:1993-01-01 00:00:00
abstract::Erythritol is a sugar alcohol produced by Aureobasidium sp. from glucose. It is 75-80% as sweet as sucrose and is also nonhygroscopic. The aim of this study was to evaluate this sugar substitute from a cariological point of view. Erythritol was neither utilized as a substrate for the lactic acid production nor for pla...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261468
更新日期:1992-01-01 00:00:00
abstract::The crowns of 60 permanent human molars were sectioned transversally. The exposed dentin surface was divided into different parts: a first part was kept as control, a second part was immediately varnished, and a third part was irradiated with a CO2 laser using the same irradiation conditions as those applied for carie...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261438
更新日期:1992-01-01 00:00:00
abstract::Some newly designed surface-active phosphates were investigated with respect to their capacity to inhibit caries lesion formation in vitro. On the labial or buccal surfaces of sound human third molars, windows were prepared for investigation. One half of each window was treated with the test compound at pH values of 7...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261434
更新日期:1992-01-01 00:00:00
abstract::Nine-day-old rats were given oral fluoride doses (0.5 micrograms F/g body weight). Plasma, enamel organ, muscle and liver samples were collected from nondosed pups (baseline) and 15, 30, 60 and 120 min after the dose. Samples were assayed for fluoride and calcium concentrations. Adult rats were given 20 ppm F water fo...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261449
更新日期:1992-01-01 00:00:00
abstract::This study was undertaken to examine the influence of occlusion on the fluoride distribution in cementum following an experiment in which the occlusion in rats was locally altered by extracting the upper left molar. These and control rats with normal occlusion were given water containing 0 or 100 ppm fluoride for 12 w...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261480
更新日期:1992-01-01 00:00:00
abstract::In 90, 60- to 80-year-old patients with teeth retained in both jaws (mean 20.4 +/- 4.3), a total of 1,092 root surface lesions were recorded. Of these 156 were diagnosed as active caries lesions, whereas 509 were considered inactive, and 427 were filled. About 60% of the elderly had one or more active lesions and 79% ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261396
更新日期:1991-01-01 00:00:00
abstract::The effect of 2-O-stearoyl glycerol-1,3-bisphosphate (Glydip) on caries lesion formation in root surfaces of sound human third molars was investigated in vitro. For this purpose parts of the root surfaces were treated with Glydip. Adjacent parts of the surfaces were not treated and served as control. Lesions were obta...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261374
更新日期:1991-01-01 00:00:00
abstract::A constant-composition fluoride (F) titration method was used to measure the amount of leachable F deposited on tooth surfaces in vitro by a 1-min rinse with a 228-ppm F solution (12 mmol/l sodium fluoride). The mean F uptake was 0.23 +/- (SE) 0.07 microgram/cm2, corresponding to less than 0.2% of the F contained in t...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261400
更新日期:1991-01-01 00:00:00
abstract::Starting in 1969, periodic cross-sectional examinations of schoolchildren have been carried out in the city of The Hague. In 1989 the periodic examinations were continued and, in general, caries prevalence was found to be very low; D3MFS values ranged between 1.5 and 2.2 at age 11.8 years. Compared to 1984, 5-year-old...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261412
更新日期:1991-01-01 00:00:00
abstract::The aim was to study the effect of substitution of invert sugar for sucrose, in combination with fluoride varnish (Duraphat) treatment twice a year, on caries development in preschool children. One hundred and eighty-seven 4-years-olds were divided randomly into four sugar groups: (1) sucrose (S), (2) sucrose-Duraphat...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000261381
更新日期:1991-01-01 00:00:00
abstract::Surface prismatic and aprismatic human enamel and unpolished or diamond-polished specimens of bovine enamel, with test and control surfaces on each studied block, were immersed in phosphoric acid containing cola beverage (pH 2.6) and citric or malic acid containing sports drinks (pH 2.8 and 3.4, respectively) for 15-1...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261348
更新日期:1991-01-01 00:00:00
abstract::Intact human enamel was demineralized in vitro to obtain artificial caries lesions. Part of the lesions was then treated with different surface-active compounds and remineralized with a remineralizing solution. The other part of the lesions was de- and remineralized in the same way, but was not treated with a surface-...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261339
更新日期:1991-01-01 00:00:00
abstract::The development of approximal carious lesions was monitored on annual bite-wing radiographs obtained from 315 children, participating in a controlled dentifrice trial; 157 of these children had used a dentifrice containing 250 ppm F and 158 a dentifrice containing 1,000 ppm F (both as NaF) during a 3-year period as th...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261369
更新日期:1991-01-01 00:00:00
abstract::The effect of supplementing the diet or drinking water with lactate dehydrogenase (LDH) on the formation of caries lesions in rats was investigated. Addition of LDH [20 and 5 mg/kg in the high-sucrose (65%) diet, 2 and 1 U/ml in the drinking water (LDH-specific activity 735 U/mg solid)] resulted in significant reducti...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261236
更新日期:1990-01-01 00:00:00
abstract::The aim of this study was to test the clinical effects of preventive regimens using fluoride and chlorhexidine on caries development in abutment teeth in patients with overdentures. 30 patients with immediate overdentures were distributed at random among three experimental groups. In these groups three different gels ...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000261298
更新日期:1990-01-01 00:00:00
abstract::To estimate permeability properties of bovine dental enamel, complex impedance measurements and radioisotope diffusion experiments were carried out before and after X-ray irradiation (single dose, 72 Gy) of enamel specimens. Neither impedance measurements nor diffusion experiments showed significant changes in permeab...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261260
更新日期:1990-01-01 00:00:00
abstract::Some antimicrobial compounds were tested for their antiplaque activity by a simple method involving measurement of the weight of Streptococcus sobrinus plaque on a glass surface. Chlorhexidine, cetylpyridinium chloride, and n-tetradecylamine reduced the weight of plaque produced by S. sobrinus in vitro; some N-palmity...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261250
更新日期:1990-01-01 00:00:00
abstract::Postradiation caries is usually prevented by the application of topical fluorides (F) at high concentrations. The aim of this study was to develop an optimal preventive program for postradiation caries by evaluating the effects of F concentration and application procedures in subjects with radiation-related xerostomia...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261173
更新日期:1989-01-01 00:00:00
abstract::Two fractions of water-soluble glucans with different molecular weight were produced by Streptococcus mutans IB. The larger glucan had a molecular weight of about 40,000. The molecular weight of the small glucan was estimated to be 4,100 by gel filtration chromatography and by biochemical methods. These glucans were t...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261188
更新日期:1989-01-01 00:00:00
abstract::Effects of zinc and/or fluoride on growth, glycolysis and survival of Streptococcus mutans GS-5 were examined in vitro. Zinc inhibited growth and glycolysis, and enhanced the antimetabolic activity of fluoride. Zinc alone had little effect on cell survival. During cell growth without pH control a protection from cell ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261149
更新日期:1989-01-01 00:00:00
abstract::Ion-sensitive field-effect transistor (ISFET) pH electrodes were used to monitor changes in plaque pH at the base of artificial occlusal surface fissures and at interproximal sites. Bovine enamel was used to construct fissures (1.5 x 0.1 x 1.0 mm) containing a small ISFET electrode. The fissures were fixed to carrier ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261220
更新日期:1989-01-01 00:00:00
abstract::Comprehensive oral examinations carried out over a period of about 10 years on participants in the Veterans Administration Dental Longitudinal Study were evaluated to identify teeth extracted during this time and to ascertain the apparent reason for these extractions. The study population included 736 dentulous adult ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261178
更新日期:1989-01-01 00:00:00
abstract::Oral exposed, natural root surfaces of extracted human teeth were subjected to artificial lesion formation in gels of dialyzed gelatin that contained 75 mM lactic and 25 mM acetic acid and 1, 3, 10, 32, 100, 320, 550, or 1,000 mg F/l at pH 4.3-4.4 and at 36 degrees C. Ca and PO4 demineralization per square millimeter ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261096
更新日期:1988-01-01 00:00:00